Effect of different levels of mannan‐oligosaccharide supplementation on some immunological variables in weaned piglets
Identifieur interne : 000E06 ( Main/Exploration ); précédent : 000E05; suivant : 000E07Effect of different levels of mannan‐oligosaccharide supplementation on some immunological variables in weaned piglets
Auteurs : I. Nochta [Hongrie] ; T. Tuboly [Hongrie] ; V. Halas [Hongrie] ; L. Babinszky [Hongrie]Source :
- Journal of Animal Physiology and Animal Nutrition [ 0931-2439 ] ; 2009-08.
English descriptors
- Teeft :
- Animal nutrition, Animal physiology, Animal science, Antibiotic, Antibiotic supplementation, Antibiotic treatment, Antimannan antibodies, Basal diet, Blackwell verlag gmbh, Blackwell verlag gmbh effect, Blood samples, Cellular immunity, Chemical composition, Colorimetric assay, Complement system, Crude protein, Dietary treatments, Different doses, Different superscript letters, Disease virus, Experimental procedure, Feed additives, Feed industry, Fourth week, Further effect, Gmbh, Growth performance, Growth promoter, Higher doses, Highest value, Humoral, Immune, Immune function, Immune parameters, Immune response, Immune responses, Immune system, Immune variables, Interaction effect, Journal compilation, Kaposvar university, Lymphocyte, Mannan, Mannan oligosaccharide, Mannan oligosaccharides, Microbial population, Mitogen, Negative control, Nochta, Nottingham, Nottingham university press, Nutrient content, Oligosaccharide, Optical density, Pharmacological additions, Phosphorylated mannans, Physiology, Piglet, Piglet performance, Positive control, Positive control group, Poultry science, Replication effect, Rmse rmse, Same tendency, Sixth treatment, Small intestine, Square error, Statistical analysis, Supplementation, Systemic immunity, Transmissible gastroenteritis virus, Verlag, Veterinary science, Virus infection, Weanling pigs, Weekly intervals.
Abstract
The effect of different doses of mannan‐oligosaccharide (MOS) on specific and non‐specific immune responses was studied in piglets, weaned at 28 days. A total of 58 piglets were used in six groups. Five groups were fed 0, 1, 2, 4 g MOS product per kg diet or with growth promoting antibiotics and immunized by inactivated Aujeszky’s disease virus (AyV) vaccine at week 1 and 3 of the experiment (35 and 49 days). A sixth group, receiving the same non‐supplemented diets was not immunized. Blood samples for lymphocyte stimulation (LST) and AyV neutralization (VN) tests were taken from all pigs on the first day of the experiment and at weekly intervals for 5 weeks. At week 8, the immunized piglets were infected orally with transmissible gastroenteritis virus. All piglets were weighed and slaughtered at week 10, digesta from small intestine were collected and tested for the presence of secretory (s)IgA. Feeding MOS supplementation resulted in enhanced specific and non‐specific immune responses, however, a regressive dose‐response of MOS was observed. Both the specific cellular (LST) and humoral responses (VN) were enhanced after 2 weeks of feeding 1 g/kg MOS and significantly differed from the antibiotic positive control. The same tendency was detected in case of the non‐specific LSTs, although these started some weeks later showing significant differences by the fifth week. Higher doses of MOS had no further beneficial effect on systemic immunity. In addition, 1 g/kg MOS supplementation group also showed some advantage in local immune responsiveness. Therefore, based on the studied immune variables, 1 g/kg MOS product is suggested in the diet of weaned piglets.
Url:
DOI: 10.1111/j.1439-0396.2008.00835.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000628
- to stream Istex, to step Curation: 000608
- to stream Istex, to step Checkpoint: 000140
- to stream Main, to step Merge: 000E08
- to stream Main, to step Curation: 000E06
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of different levels of mannan‐oligosaccharide supplementation on some immunological variables in weaned piglets</title><author><name sortKey="Nochta, I" sort="Nochta, I" uniqKey="Nochta I" first="I." last="Nochta">I. Nochta</name></author><author><name sortKey="Tuboly, T" sort="Tuboly, T" uniqKey="Tuboly T" first="T." last="Tuboly">T. Tuboly</name></author><author><name sortKey="Halas, V" sort="Halas, V" uniqKey="Halas V" first="V." last="Halas">V. Halas</name></author><author><name sortKey="Babinszky, L" sort="Babinszky, L" uniqKey="Babinszky L" first="L." last="Babinszky">L. Babinszky</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:05498EFE87F7B79B28C78DAF0EF67300ABC5604A</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1111/j.1439-0396.2008.00835.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-HR3SHBNF-H/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000628</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000628</idno><idno type="wicri:Area/Istex/Curation">000608</idno><idno type="wicri:Area/Istex/Checkpoint">000140</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000140</idno><idno type="wicri:doubleKey">0931-2439:2009:Nochta I:effect:of:different</idno><idno type="wicri:Area/Main/Merge">000E08</idno><idno type="wicri:Area/Main/Curation">000E06</idno><idno type="wicri:Area/Main/Exploration">000E06</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Effect of different levels of mannan‐oligosaccharide supplementation on some immunological variables in weaned piglets</title><author><name sortKey="Nochta, I" sort="Nochta, I" uniqKey="Nochta I" first="I." last="Nochta">I. Nochta</name><affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country><wicri:regionArea> Agrokomplex, CSZRT, Zichyújfalu</wicri:regionArea><wicri:noRegion>Zichyújfalu</wicri:noRegion></affiliation></author><author><name sortKey="Tuboly, T" sort="Tuboly, T" uniqKey="Tuboly T" first="T." last="Tuboly">T. Tuboly</name><affiliation wicri:level="3"><country xml:lang="fr">Hongrie</country><wicri:regionArea> Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Szent István University, Budapest</wicri:regionArea><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Halas, V" sort="Halas, V" uniqKey="Halas V" first="V." last="Halas">V. Halas</name><affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country><wicri:regionArea> Department of Animal Nutrition, Faculty of Animal Science, Kaposvár University, Kaposvár</wicri:regionArea><wicri:noRegion>Kaposvár</wicri:noRegion></affiliation></author><author><name sortKey="Babinszky, L" sort="Babinszky, L" uniqKey="Babinszky L" first="L." last="Babinszky">L. Babinszky</name><affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country><wicri:regionArea> Department of Animal Nutrition, Faculty of Animal Science, Kaposvár University, Kaposvár</wicri:regionArea><wicri:noRegion>Kaposvár</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Animal Physiology and Animal Nutrition</title><title level="j" type="alt">JOURNAL OF ANIMAL PHYSIOLOGY ANIMAL NUTRITION</title><idno type="ISSN">0931-2439</idno><idno type="eISSN">1439-0396</idno><imprint><biblScope unit="vol">93</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="496">496</biblScope><biblScope unit="page" to="504">504</biblScope><biblScope unit="page-count">9</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2009-08">2009-08</date></imprint><idno type="ISSN">0931-2439</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0931-2439</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Animal nutrition</term><term>Animal physiology</term><term>Animal science</term><term>Antibiotic</term><term>Antibiotic supplementation</term><term>Antibiotic treatment</term><term>Antimannan antibodies</term><term>Basal diet</term><term>Blackwell verlag gmbh</term><term>Blackwell verlag gmbh effect</term><term>Blood samples</term><term>Cellular immunity</term><term>Chemical composition</term><term>Colorimetric assay</term><term>Complement system</term><term>Crude protein</term><term>Dietary treatments</term><term>Different doses</term><term>Different superscript letters</term><term>Disease virus</term><term>Experimental procedure</term><term>Feed additives</term><term>Feed industry</term><term>Fourth week</term><term>Further effect</term><term>Gmbh</term><term>Growth performance</term><term>Growth promoter</term><term>Higher doses</term><term>Highest value</term><term>Humoral</term><term>Immune</term><term>Immune function</term><term>Immune parameters</term><term>Immune response</term><term>Immune responses</term><term>Immune system</term><term>Immune variables</term><term>Interaction effect</term><term>Journal compilation</term><term>Kaposvar university</term><term>Lymphocyte</term><term>Mannan</term><term>Mannan oligosaccharide</term><term>Mannan oligosaccharides</term><term>Microbial population</term><term>Mitogen</term><term>Negative control</term><term>Nochta</term><term>Nottingham</term><term>Nottingham university press</term><term>Nutrient content</term><term>Oligosaccharide</term><term>Optical density</term><term>Pharmacological additions</term><term>Phosphorylated mannans</term><term>Physiology</term><term>Piglet</term><term>Piglet performance</term><term>Positive control</term><term>Positive control group</term><term>Poultry science</term><term>Replication effect</term><term>Rmse rmse</term><term>Same tendency</term><term>Sixth treatment</term><term>Small intestine</term><term>Square error</term><term>Statistical analysis</term><term>Supplementation</term><term>Systemic immunity</term><term>Transmissible gastroenteritis virus</term><term>Verlag</term><term>Veterinary science</term><term>Virus infection</term><term>Weanling pigs</term><term>Weekly intervals</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The effect of different doses of mannan‐oligosaccharide (MOS) on specific and non‐specific immune responses was studied in piglets, weaned at 28 days. A total of 58 piglets were used in six groups. Five groups were fed 0, 1, 2, 4 g MOS product per kg diet or with growth promoting antibiotics and immunized by inactivated Aujeszky’s disease virus (AyV) vaccine at week 1 and 3 of the experiment (35 and 49 days). A sixth group, receiving the same non‐supplemented diets was not immunized. Blood samples for lymphocyte stimulation (LST) and AyV neutralization (VN) tests were taken from all pigs on the first day of the experiment and at weekly intervals for 5 weeks. At week 8, the immunized piglets were infected orally with transmissible gastroenteritis virus. All piglets were weighed and slaughtered at week 10, digesta from small intestine were collected and tested for the presence of secretory (s)IgA. Feeding MOS supplementation resulted in enhanced specific and non‐specific immune responses, however, a regressive dose‐response of MOS was observed. Both the specific cellular (LST) and humoral responses (VN) were enhanced after 2 weeks of feeding 1 g/kg MOS and significantly differed from the antibiotic positive control. The same tendency was detected in case of the non‐specific LSTs, although these started some weeks later showing significant differences by the fifth week. Higher doses of MOS had no further beneficial effect on systemic immunity. In addition, 1 g/kg MOS supplementation group also showed some advantage in local immune responsiveness. Therefore, based on the studied immune variables, 1 g/kg MOS product is suggested in the diet of weaned piglets.</div></front></TEI><affiliations><list><country><li>Hongrie</li></country><region><li>Hongrie centrale</li></region><settlement><li>Budapest</li></settlement></list><tree><country name="Hongrie"><noRegion><name sortKey="Nochta, I" sort="Nochta, I" uniqKey="Nochta I" first="I." last="Nochta">I. Nochta</name></noRegion><name sortKey="Babinszky, L" sort="Babinszky, L" uniqKey="Babinszky L" first="L." last="Babinszky">L. Babinszky</name><name sortKey="Halas, V" sort="Halas, V" uniqKey="Halas V" first="V." last="Halas">V. Halas</name><name sortKey="Tuboly, T" sort="Tuboly, T" uniqKey="Tuboly T" first="T." last="Tuboly">T. Tuboly</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E06 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000E06 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:05498EFE87F7B79B28C78DAF0EF67300ABC5604A
|texte= Effect of different levels of mannan‐oligosaccharide supplementation on some immunological variables in weaned piglets
}}
| This area was generated with Dilib version V0.6.33. |  |